Chaparral is claimed to help treat over 50 ailments, including cancer, arthritis, tuberculosis, skin conditions, and the common cold.
 
Chaparral contains various potent compounds that may interact with cancer pathways.
 
In particular, chaparral leaves and stems contain nordihydroguaiaretic acid (NDGA), a potent antioxidant linked to tumor regression — the shrinkage of tumors
 
Antiviral activity
There are claims that the chaparral herb can prevent the replication of the human papillomavirus (HPV), human immunodeficiency virus (HIV), and herpes simplex virus (HSV).
 
Chaparral contains many different polyphenols called lignans, which are plant compounds that confer health benefits. The lignans in chaparral are believed to block transcription factor Sp1, which is responsible for replicating virus genes. Although this is promising, chaparral may cause dangerous side effects, including liver complications, diarrhea, and fever, which are especially dangerous for people with compromised immune systems, including those with HIV.
 
Furthermore, there is no human research available, making it difficult to know its true effectiveness.
Anti-inflammatory activity
Chaparral contains NDGA, an antioxidant that can inhibit lipid peroxidation. This is a process in which molecules called free radicals attack lipids, resulting in cellular damage. Cellular damage may increase the risk of chronic diseases such as neurodegenerative disease.